http://www.ncbi.nlm.nih.gov/pubmed/?term=berger%27s+disease
Jos munuaisoireileva gluteeniallerginen haluaa ajatella myös munuaistaan,dieetin pitää olla tarkka eikä saa tehdä dieettipoikkeuksia, vaikka suolisto kestäisikin sellaisen. Ei kannata käyttää kauraa eikä vehnätärkkelysperäisiä gluteenittomia valmisteita. Siis koetettava tosiaankin välttää gluteenia ja katsoa että verenpaine on normaali, virtsassa ei ole valkuaista ja turvotuksia ei tule jalkaan eikä yleistä pöhöttymistä kudoksiin. Kannattaa myös juoda säännöllisesti puhdasta vettä, eikä odottele, että selkä jomottaa veden vajeesta ennenkuin juo vettä. Veden jano voi nimittäin olla keliaakikolla epäsuhteessa veden tarpeeseen.
Tämä gluteenittomalla ruoalla hoituva Bergerin tauti on IgA-nefropatia.
fredag 22 april 2016
Gliadiini antigeenina ja munuainen
IHMISELLÄ: coeliac disease and IgA-nephropathy/Berger's disease
IgA-gliadin antibodies, IgA-containing circulating immune complexes, and IgA glomerular deposits in wasting marmoset syndrome.
IgA-gliadin antibodies, IgA-containing circulating immune complexes, and IgA glomerular deposits in wasting marmoset syndrome.
Schroeder C, Osman AA, Roggenbuck D, Mothes T.
Nephrol Dial Transplant. 1999 Aug;14(8):1875-80.
- PMID:
- 10462265
2.
Brack M, Schroeder C, Fooke M, Schlumberger W.
Nephron. 1999;82(3):221-31.
3.
Barsoum R, Nabil M, Saady G, Genin C, Saleh E, Francis M, el-Kalioubi A, Iskander I, el-Garem A.
Kidney Int. 1996 Sep;50(3):920-8.
4.
Coppo R, Amore A, Gianoglio B, Porcellini MG, Peruzzi L, Reyna A, Gusmano R, Giani M, Sereni F, Gianviti A, et al.
Minerva Urol Nefrol. 1994 Mar;46(1):49-54. Italian.
5.
O'Donoghue DJ, Jewkes F, Postlethwaite RJ, Ballardie FW.
Clin Sci (Lond). 1992 Sep;83(3):281-7.
- PMID:
- 1327645
6.
Coppo R, Amore A, Roccatello D.
J Am Soc Nephrol. 1992 Apr;2(10 Suppl):S173-80. Review.
To investigate the role of dietary components in immunoglobulin A mesangial nephropathy (IgAGN), this study focused on gliadin,
based on the reported association between coeliac disease and IgAGN as
well as the pilot observation that a gluten-free diet was able to reduce
the levels of circulating IgA immune complexes (IgAIC). IgA mesangial
deposits in mice were induced by oral immunization with gliadin and in rats by inducing alcoholic liver cirrhosis, which increased the levels of IgA against dietary antigens (Ag). Gliadin
was able to bind to cultured mesangial cells by a lectinic bond, which
was reversed by competitive sugars. Binding increased mesangial cell
tumor necrosis factor synthesis and decreased prostaglandin E2
production. Several gluten lectinic fractions modulate leukocyte
oxidative metabolism, cytotoxicity, and chemotaxis. In IgAGN patients,
serum IgA to dietary Ag were sporadically positive and IgAIC containing
IgA to dietary components were significantly increased. The affinity of
serum IgA to various lectins was increased in some patients. Conversely,
no substantial deposition in renal tissue of dietary Ags was observed
by immunofluorescence. A gluten-free diet, given to IgAGN patients with
high levels of circulating IgAIC and positive antigliadin IgA, was
followed by a decrease in the mean levels of both IgAIC and IgA to
various dietary Ag, parallel to a reduction in proteinuria. These data
suggest that dietary components, such as Ag or lectins, may play a role
in IgAGN by promoting IgAIC formation and perhaps favoring mesangial
localization via lectinic interactions.
7.
Emancipator SN, Rao CS, Amore A, Coppo R, Nedrud JG.
J Am Soc Nephrol. 1992 Apr;2(10 Suppl):S149-58. Review.
- PMID:
- 1600131
8.
Primary IgA nephropathy: the relevance of experimental models in the understanding of human disease.
Montinaro V, Gesualdo L, Schena FP.
Nephron. 1992;62(4):373-81. Review.
- PMID:
- 1300432
9.
Coppo R, Amore A, Roccatello D, Gianoglio B, Peruzzi L, Alessi D, Reyna A, Mesiti A, Piccoli G, Sena LM.
Minerva Urol Nefrol. 1991 Jul-Sep;43(3):171-4. Italian.
10.
Coppo R, Mazzucco G, Martina G, Roccatello D, Amore A, Novara R, Bargoni A, Piccoli G, Sena LM.
Lab Invest. 1989 Apr;60(4):499-506.
- PMID:
- 2709812
11.
Fornasieri A, Sinico RA, Maldifassi P, Paterna L, Benuzzi S, Colasanti G, D'Amico G.
Nephrol Dial Transplant. 1988;3(6):738-43.
- PMID:
- 3147415
Etiketter:
Munuainen ja anti-gliadiinivasta-aineet
Prenumerera på:
Inlägg (Atom)